MolNFT v1 · #70268 · protein

Crystal structure of fructosyltransferase (wild-type) from a. japonicus in complex with glucose

3LFI: “Crystal structure of fructosyltransferase (wild-type) from a. japonicus in complex with glucose”. X-ray diffraction, 1 ligand (BGC), 15 pockets (best druggability 0.76). MolNFT v1 #70268 on GenesisL1: 3D structure, binding sites and…

PDB: 3LFI
Type: protein
Length: 1,268 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fructosyltransferase
Ligands: BGC
Pockets: 15 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 10% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Fructosyltransferase	protein	634	10% helix, 43% strand	—

Ligands and binding sites

BGC · beta-D-glucopyranose · sugar · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

15 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	105	0.76	0.96	22	empty
2	59	0.75	1.00	19	empty
3	64	0.75	0.99	19	empty
4	438	0.70	0.81	37	BGC
5	445	0.68	0.80	41	BGC

Interfaces

1 interface between chains.

A–B · 946 Å² buried · 12 hydrogen bonds · protein-protein

Compared structures

3LFI · Crystal structure of fructosyltransferase (wild-type) from A. japonicus in complex with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 3LFI · PDBe 3LFI

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