MolNFT v1 · #69943 · protein
The crystal structure of human haloacid dehalogenase-like hydrolase domain containing 1A (HDHD1A)
3L5K · Haloacid dehalogenase-like hydrolase domain-containing…: “The crystal structure of human haloacid dehalogenase-like hydrolase domain containing 1A (HDHD1A)”. X-ray diffraction, 2 ligands (K, CL), 1 pocket (best druggability 0.75).…
- PDB
- 3L5K
- Type
- protein
- Length
- 233 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Haloacid dehalogenase-like hydrolase domain-containing protein 1A
- UniProt
- Q08623
- Ligands
- K, CL
- Pockets
- 1 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Haloacid dehalogenase-like hydrolase domain-containing protein 1A | protein | 233 | 44% helix, 12% strand | Q08623 |
Ligands and binding sites
- K · Potassium ion · metal · chains A
- CL · Chloride ion · ion · 4 copies · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 569 | 0.75 | 0.82 | 60 | K, CL |
Compared structures
- 3L5K · The crystal structure of human Haloacid Dehalogenase-like Hydrolase Domain containing 1A… · the same entry in another collection · chain A against A, TM-score 1.00
- Q08623 · AlphaFold monomer V2.0 prediction for pseudouridine-5'-phosphatase (Q08623) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q08623
- Elsewhere: RCSB PDB 3L5K · PDBe 3L5K · UniProt Q08623
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