MolNFT v1 · #6951 · protein

Glucosamine-6-phosphate deaminase from E.COLI, T conformer, at 2.2A resolution

1FS6: “Glucosamine-6-phosphate deaminase from E.COLI, T conformer, at 2.2A resolution”. X-ray diffraction, 1 pocket (best druggability 0.71). MolNFT v1 #6951 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1FS6
Type: protein
Length: 266 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glucosamine-6-phosphate deaminase
EC: 5.3.1.10
UniProt: P0A759
Pockets: 1 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glucosamine-6-phosphate deaminase (EC 5.3.1.10)	protein	266	40% helix, 15% strand	P0A759

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	367	0.71	0.83	42	empty

Compared structures

1FS6 · Glucosamine-6-phosphate deaminase from E.COLI, T conformer, at 2.2A resolution · the same entry in another collection · chain A against A, TM-score 1.00
P0A759 · AlphaFold monomer V2.0 prediction for glucosamine-6-phosphate deaminase (P0A759) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A759
Elsewhere: RCSB PDB 1FS6 · PDBe 1FS6 · UniProt P0A759

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