MolNFT v1 · #69134 · protein
Crystal structure of the RAS-association (ra) domain of ralgds
3KH0 · Ral guanine nucleotide dissociation stimulator: “Crystal structure of the RAS-association (ra) domain of ralgds”. X-ray diffraction, 1 ligand (UNX), 1 pocket (best druggability 0.43). MolNFT v1 #69134 on GenesisL1: 3D structure…
- PDB
- 3KH0
- Type
- protein
- Length
- 207 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ral guanine nucleotide dissociation stimulator
- UniProt
- Q12967
- Ligands
- UNX
- Pockets
- 1 · best druggability 0.43
Structure
x-ray diffraction · 2 distinct chains · 17% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ral guanine nucleotide dissociation stimulator | protein | 102 | 18% helix, 38% strand | Q12967 |
| B | Ral guanine nucleotide dissociation stimulator | protein | 105 | 17% helix, 36% strand | Q12967 |
Ligands and binding sites
- UNX · Unknown atom or ion · ion · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 210 | 0.43 | 0.72 | 29 | empty |
Interfaces
1 interface between chains.
- A–B · 564 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 3KH0 · Crystal structure of the Ras-association (RA) domain of RALGDS · the same entry in another collection · chain A against A, TM-score 1.00
- Q12967 · AlphaFold monomer V2.0 prediction for ral guanine nucleotide dissociation stimulator… · a predicted model of the same protein · chain A against A, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12967
- Elsewhere: RCSB PDB 3KH0 · PDBe 3KH0 · UniProt Q12967
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