MolNFT v1 · #68513 · protein
Crystal structure of the rets periplasmic domain
3JYB · Sensor protein: “Crystal structure of the rets periplasmic domain”. X-ray diffraction, 2 pockets (best druggability 0.61). MolNFT v1 #68513 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3JYB
- Type
- protein
- Length
- 276 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sensor protein
- EC
- 2.7.13.3
- UniProt
- Q9HUV7
- Pockets
- 2 · best druggability 0.61
Structure
x-ray diffraction · 1 distinct chain · 9% helix, 46% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Sensor protein (EC 2.7.13.3) | protein | 138 | 9% helix, 46% strand | Q9HUV7 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 177 | 0.61 | 0.83 | 33 | empty |
| 2 | 157 | 0.46 | 0.76 | 26 | empty |
Interfaces
1 interface between chains.
- A–B · 669 Ų buried · 4 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 3JYB · Crystal Structure of the RetS periplasmic domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HUV7
- Elsewhere: RCSB PDB 3JYB · PDBe 3JYB · UniProt Q9HUV7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.