MolNFT v1 · #68099 · protein
Capsid expansion mechanism of bacteriophage T7 revealed by multi-state atomic models derived from cryo-EM reconstructions
3J7W · Major capsid protein 10A: “Capsid expansion mechanism of bacteriophage T7 revealed by multi-state atomic models derived from cryo-EM…”. Electron microscopy, 20 pockets (best druggability 0.68). MolNFT v1 #68099 on GenesisL1: 3D…
- PDB
- 3J7W
- Type
- protein
- Length
- 2,401 residues
- Chains
- 7
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Major capsid protein 10A
- UniProt
- P19726
- Pockets
- 20 · best druggability 0.68
Structure
electron microscopy · 1 distinct chain · 20% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G | Major capsid protein 10A | protein | 343 | 20% helix, 22% strand | P19726 |
Pockets
20 pockets found on a 1 Å grid, 13 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 505 | 0.68 | 0.79 | 67 | empty |
| 2 | 471 | 0.64 | 0.77 | 57 | empty |
| 3 | 436 | 0.62 | 0.76 | 57 | empty |
| 4 | 70 | 0.61 | 0.91 | 18 | empty |
| 5 | 168 | 0.61 | 0.83 | 33 | empty |
Interfaces
13 interfaces between chains.
- E–F · 3035 Ų buried · 25 hydrogen bonds · protein-protein
- B–C · 2998 Ų buried · 31 hydrogen bonds · protein-protein
- C–D · 2980 Ų buried · 31 hydrogen bonds · protein-protein
- D–E · 2963 Ų buried · 29 hydrogen bonds · protein-protein
- A–F · 2940 Ų buried · 31 hydrogen bonds · protein-protein
Compared structures
- 3J7W · Capsid Expansion Mechanism Of Bacteriophage T7 Revealed By Multi-State Atomic Models… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19726
- Elsewhere: RCSB PDB 3J7W · PDBe 3J7W · UniProt P19726
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