MolNFT v1 · #67947 · protein
Lidless D386A mm-cpn in the pre-hydrolysis ATP-bound state
3J02 · Lidless D386A mm-cpn variant: “Lidless D386A mm-cpn in the pre-hydrolysis ATP-bound state”. Electron microscopy, 20 pockets (best druggability 0.83). MolNFT v1 #67947 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3J02
- Type
- protein
- Length
- 7,856 residues
- Chains
- 16
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lidless D386A mm-cpn variant
- UniProt
- Q877G8
- Pockets
- 20 · best druggability 0.83
Structure
electron microscopy · 1 distinct chain · 53% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | Lidless D386A mm-cpn variant | protein | 491 | 53% helix, 18% strand | Q877G8 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1011 | 0.83 | 0.84 | 89 | empty |
| 2 | 1010 | 0.83 | 0.84 | 93 | empty |
| 3 | 1044 | 0.83 | 0.84 | 85 | empty |
| 4 | 1099 | 0.83 | 0.84 | 107 | empty |
| 5 | 1165 | 0.83 | 0.84 | 110 | empty |
Interfaces
24 interfaces between chains.
- N–O · 757 Ų buried · 7 hydrogen bonds · protein-protein
- B–C · 755 Ų buried · 7 hydrogen bonds · protein-protein
- A–B · 755 Ų buried · 7 hydrogen bonds · protein-protein
- O–P · 754 Ų buried · 7 hydrogen bonds · protein-protein
- M–N · 754 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 3J02 · Lidless D386A Mm-cpn in the pre-hydrolysis ATP-bound state · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q877G8
- Elsewhere: RCSB PDB 3J02 · PDBe 3J02 · UniProt Q877G8
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