MolNFT v1 · #67946 · protein + RNA
Models for ribosome components that are nearest neighbors to the bovine mitochondrial initiation FACTOR2 bound to the E. COLI ribosome
3IZZ · Helix 5, 14, 15 (small subunit): “Models for ribosome components that are nearest neighbors to the bovine mitochondrial initiation FACTOR2…”. Electron microscopy, 15 pockets (best druggability 0.61). MolNFT v1 #67946 on GenesisL1…
- PDB
- 3IZZ
- Type
- protein + RNA
- Length
- 582 residues
- Chains
- 6
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Helix 5, 14, 15 (small subunit); Helix 18 (small subunit); Helix 44 (small subunit)…
- Pockets
- 15 · best druggability 0.61
Structure
electron microscopy · 6 distinct chains · 6% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Helix 5, 14, 15 (small subunit) | rna | 59 | — | — |
| D | Helix 18 (small subunit) | rna | 60 | — | — |
| E | Helix 44 (small subunit) | rna | 100 | — | — |
| F | Protein S12 (small subunit) | protein | 124 | 9% helix, 23% strand | — |
| B | Helix 69, 71, 89, 92, 95 (large subunit) | rna | 118 | — | — |
| G | Protein L14 (large subunit) | protein | 121 | 2% helix, 21% strand | — |
Pockets
15 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 720 | 0.61 | 0.73 | 48 | empty |
| 2 | 470 | 0.59 | 0.75 | 25 | empty |
| 3 | 332 | 0.55 | 0.75 | 29 | empty |
| 4 | 120 | 0.49 | 0.81 | 25 | empty |
| 5 | 292 | 0.49 | 0.73 | 32 | empty |
Interfaces
7 interfaces between chains.
- E–B · 1292 Ų buried · 359 hydrogen bonds · nucleic-nucleic
- D–F · 1132 Ų buried · 49 hydrogen bonds · protein-nucleic
- B–G · 562 Ų buried · 3 hydrogen bonds · protein-nucleic
- A–G · 184 Ų buried · 6 hydrogen bonds · protein-nucleic
- E–G · 168 Ų buried · 2 hydrogen bonds · protein-nucleic
Compared structures
- 3IZZ · Models for ribosome components that are nearest neighbors to the bovine mitochondrial… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 3IZZ · PDBe 3IZZ
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.