MolNFT v1 · #67898 · protein

Variable domains of the computer generated model (wam) of Fab 8 fitted into the cryoem reconstruction of the virus-Fab 8 complex

3IY3 · Antibody fragment from neutralizing antibody 8 (light chain): “Variable domains of the computer generated model (wam) of Fab 8 fitted into the cryoem reconstruction of the…”. Electron microscopy, 2 pockets (best druggability 0.31).…

PDB: 3IY3
Type: protein
Length: 232 residues
Chains: 2
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Antibody fragment from neutralizing antibody 8 (light chain); Antibody fragment from…
Pockets: 2 · best druggability 0.31

Structure

electron microscopy · 2 distinct chains · 6% helix, 53% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Antibody fragment from neutralizing antibody 8 (light chain)	protein	113	3% helix, 53% strand	—
B	Antibody fragment from neutralizing antibody 8 (heavy chain)	protein	119	10% helix, 52% strand	—

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	64	0.31	0.75	16	empty
2	60	0.25	0.72	16	empty

Interfaces

1 interface between chains.

A–B · 726 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

3IY3 · Variable domains of the computer generated model (WAM) of Fab 8 fitted into the cryoEM… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 3IY3 · PDBe 3IY3

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