MolNFT v1 · #67706 · protein

Structure of non-mineralized bfrb (as-isolated) from pseudomonas aeruginosa to 2.07A resolution

3ISF · Bacterioferritin: “Structure of non-mineralized bfrb (as-isolated) from pseudomonas aeruginosa to 2.07A resolution”. X-ray diffraction, 2 ligands (HEM, K), 11 pockets (best druggability 0.71). MolNFT v1 #67706 on GenesisL1: 3D…

PDB: 3ISF
Type: protein
Length: 933 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Bacterioferritin
UniProt: Q9HY79
Ligands: HEM, K
Pockets: 11 · best druggability 0.71

Structure

x-ray diffraction · 3 distinct chains · 79% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, E, F	Bacterioferritin	protein	155	79% helix, 0% strand	Q9HY79
C	Bacterioferritin	protein	156	79% helix, 0% strand	Q9HY79
D	Bacterioferritin	protein	157	78% helix, 0% strand	Q9HY79

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · 4 copies · chains A, B, C, D, E, F
K · Potassium ion · metal · 2 copies · chains A, D, B, E, F

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	204	0.71	0.87	33	HEM
2	219	0.69	0.86	34	HEM
3	345	0.58	0.76	34	empty
4	320	0.57	0.76	33	empty
5	95	0.42	0.78	17	empty

Interfaces

8 interfaces between chains.

A–B · 923 Å² buried · 11 hydrogen bonds · protein-protein
C–D · 903 Å² buried · 11 hydrogen bonds · protein-protein
B–D · 533 Å² buried · 8 hydrogen bonds · protein-protein
A–D · 519 Å² buried · 6 hydrogen bonds · protein-protein
B–F · 517 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

3ISF · Structure of non-mineralized Bfrb (as-isolated) from Pseudomonas aeruginosa to 2.07A… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9HY79
Elsewhere: RCSB PDB 3ISF · PDBe 3ISF · UniProt Q9HY79

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.