MolNFT v1 · #67691 · protein

Crystal structure of functional region of uafa from staphylococcus saprophyticus in the presence of cholesterol

3IS0 · Uro-adherence factor a: “Crystal structure of functional region of uafa from staphylococcus saprophyticus in the presence of…”. X-ray diffraction, 3 pockets (best druggability 0.53). MolNFT v1 #67691 on GenesisL1: 3D structure…

PDB: 3IS0
Type: protein
Length: 392 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uro-adherence factor a
UniProt: Q4A0V8
Pockets: 3 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 53% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Uro-adherence factor a	protein	392	6% helix, 53% strand	Q4A0V8

Ligands and binding sites

GOL · Glycerol · additive · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	137	0.53	0.81	23	empty
2	225	0.51	0.76	33	empty
3	75	0.33	0.75	13	empty

Compared structures

3IS0 · Crystal structure of functional region of UafA from Staphylococcus saprophyticus in the… · the same entry in another collection · chain X against X, TM-score 1.00
Q4A0V8 · AlphaFold monomer V2.0 prediction for uro-adherence factor a (Q4A0V8) · a predicted model of the same protein · chain X against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4A0V8
Elsewhere: RCSB PDB 3IS0 · PDBe 3IS0 · UniProt Q4A0V8

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.