MolNFT v1 · #67434 · protein

The structure of a conserved protein from streptococcus mutans UA159.

3IKB · Uncharacterized conserved protein: “The structure of a conserved protein from streptococcus mutans UA159.”. X-ray diffraction, 8 pockets (best druggability 0.67). MolNFT v1 #67434 on GenesisL1: 3D structure, binding sites and…

PDB: 3IKB
Type: protein
Length: 392 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized conserved protein
UniProt: Q8DTT5
Pockets: 8 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Uncharacterized conserved protein	protein	196	48% helix, 10% strand	Q8DTT5

Ligands and binding sites

FLC · Citrate anion · additive · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	369	0.67	0.80	36	empty
2	469	0.66	0.78	46	empty
3	228	0.53	0.77	36	FLC
4	178	0.52	0.78	25	FLC
5	86	0.41	0.78	15	empty

Interfaces

1 interface between chains.

A–B · 696 Å² buried · 7 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 10 modified (engineered).

Compared structures

3IKB · The structure of a conserved protein from Streptococcus mutans UA159. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8DTT5
Elsewhere: RCSB PDB 3IKB · PDBe 3IKB · UniProt Q8DTT5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.