MolNFT v1 · #67318 · protein
1.85 ångström resolution crystal structure of transaldolase B (tala) from francisella tularensis.
3IGX: “1.85 ångström resolution crystal structure of transaldolase B (tala) from francisella tularensis.”. X-ray diffraction, 1 ligand (PO4), 5 pockets (best druggability 0.86). MolNFT v1 #67318 on GenesisL1: 3D structure, binding sites…
- PDB
- 3IGX
- Type
- protein
- Length
- 642 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transaldolase
- EC
- 2.2.1.2
- UniProt
- Q5NFX0
- Ligands
- PO4
- Pockets
- 5 · best druggability 0.86
Structure
x-ray diffraction · 2 distinct chains · 57% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transaldolase (EC 2.2.1.2) | protein | 322 | 56% helix, 12% strand | Q5NFX0 |
| B | Transaldolase (EC 2.2.1.2) | protein | 320 | 58% helix, 12% strand | Q5NFX0 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 251 | 0.86 | 0.98 | 30 | empty |
| 2 | 58 | 0.70 | 0.97 | 18 | empty |
| 3 | 78 | 0.63 | 0.90 | 21 | empty |
| 4 | 171 | 0.51 | 0.78 | 30 | PO4 |
| 5 | 153 | 0.50 | 0.78 | 33 | PO4 |
Interfaces
1 interface between chains.
- A–B · 854 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 11 modified (engineered).
Compared structures
- 3IGX · 1.85 Angstrom Resolution Crystal Structure of Transaldolase B (talA) from Francisella… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5NFX0
- Elsewhere: RCSB PDB 3IGX · PDBe 3IGX · UniProt Q5NFX0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.