MolNFT v1 · #67282 · protein

Crystal structure of the haloferax volcanii proliferating cell nuclear antigen

3IFV · PCNA: “Crystal structure of the haloferax volcanii proliferating cell nuclear antigen”. X-ray diffraction, 1 ligand (NA), 1 pocket (best druggability 0.59). MolNFT v1 #67282 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 3IFV
Type: protein
Length: 690 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: PCNA
UniProt: D0VWY8
Ligands: NA
Pockets: 1 · best druggability 0.59

Structure

x-ray diffraction · 3 distinct chains · 24% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	PCNA	protein	216	25% helix, 43% strand	D0VWY8
B	PCNA	protein	234	23% helix, 45% strand	D0VWY8
C	PCNA	protein	240	23% helix, 46% strand	D0VWY8

Ligands and binding sites

NA · Sodium ion · metal · 9 copies · chains A, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	80	0.59	0.87	19	empty

Interfaces

3 interfaces between chains.

B–C · 641 Å² buried · 9 hydrogen bonds · protein-protein
A–C · 637 Å² buried · 10 hydrogen bonds · protein-protein
A–B · 577 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

3IFV · Crystal structure of the Haloferax volcanii proliferating cell nuclear antigen · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D0VWY8
Elsewhere: RCSB PDB 3IFV · PDBe 3IFV · UniProt D0VWY8

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