MolNFT v1 · #67162 · protein
The crystal structure of a GST-like protein from pseudomonas syringae to 2.4A
3IC8 · Uncharacterized GST-like proteinprotein: “The crystal structure of a GST-like protein from pseudomonas syringae to 2.4A”. X-ray diffraction, 18 pockets (best druggability 0.75). MolNFT v1 #67162 on GenesisL1: 3D structure, binding…
- PDB
- 3IC8
- Type
- protein
- Length
- 1,098 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized GST-like proteinprotein
- UniProt
- Q887M8
- Pockets
- 18 · best druggability 0.75
Structure
x-ray diffraction · 4 distinct chains · 41% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized GST-like proteinprotein | protein | 278 | 42% helix, 21% strand | Q887M8 |
| B | Uncharacterized GST-like proteinprotein | protein | 275 | 41% helix, 20% strand | Q887M8 |
| C | Uncharacterized GST-like proteinprotein | protein | 272 | 40% helix, 20% strand | Q887M8 |
| D | Uncharacterized GST-like proteinprotein | protein | 273 | 41% helix, 20% strand | Q887M8 |
Pockets
18 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 680 | 0.75 | 0.81 | 64 | empty |
| 2 | 472 | 0.66 | 0.78 | 45 | empty |
| 3 | 450 | 0.65 | 0.78 | 54 | empty |
| 4 | 425 | 0.61 | 0.76 | 47 | empty |
| 5 | 373 | 0.60 | 0.76 | 49 | empty |
Interfaces
5 interfaces between chains.
- A–B · 1047 Ų buried · 15 hydrogen bonds · protein-protein
- C–D · 1005 Ų buried · 6 hydrogen bonds · protein-protein
- A–C · 335 Ų buried · 3 hydrogen bonds · protein-protein
- B–D · 255 Ų buried · 3 hydrogen bonds · protein-protein
- B–C · 212 Ų buried · 2 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 24 modified, 1 isopeptide (engineered, isopeptide).
Compared structures
- 3IC8 · The Crystal Structure of a GST-like protein from Pseudomonas syringae to 2.4A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q887M8
- Elsewhere: RCSB PDB 3IC8 · PDBe 3IC8 · UniProt Q887M8
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