MolNFT v1 · #67055 · protein

Crystal structure of mycobacterium tuberculosis dutpase STOP138T mutant

3I93 · Deoxyuridine 5'-triphosphate nucleotidohydrolase: “Crystal structure of mycobacterium tuberculosis dutpase STOP138T mutant”. X-ray diffraction, 2 ligands (DUP, MG), 1 pocket (best druggability 0.35). MolNFT v1 #67055 on GenesisL1…

PDB: 3I93
Type: protein
Length: 140 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Deoxyuridine 5'-triphosphate nucleotidohydrolase
EC: 3.6.1.23
UniProt: P0A552
Ligands: DUP, MG
Pockets: 1 · best druggability 0.35

Structure

x-ray diffraction · 1 distinct chain · 5% helix, 39% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Deoxyuridine 5'-triphosphate nucleotidohydrolase (EC 3.6.1.23)	protein	140	5% helix, 39% strand	P0A552

Ligands and binding sites

DUP · 2'-deoxyuridine 5'-alpha,beta-imido-triphosphate · ligand · chains A
MG · Magnesium ion · metal · chains A
TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	67	0.35	0.77	18	empty

Compared structures

3I93 · Crystal structure of Mycobacterium tuberculosis dUTPase STOP138T mutant · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A552
Elsewhere: RCSB PDB 3I93 · PDBe 3I93 · UniProt P0A552

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.