MolNFT v1 · #66819 · protein

Crystal structure of a hit family hydrolase protein from vibrio fischeri. northeast structural genomics consortium target id VFR176

3I24: “Crystal structure of a hit family hydrolase protein from vibrio fischeri. northeast structural genomics…”. X-ray diffraction, 1 ligand (NA), 2 pockets (best druggability 0.57). MolNFT v1 #66819 on GenesisL1: 3D structure, binding…

PDB: 3I24
Type: protein
Length: 282 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hit family hydrolase
UniProt: Q5E3V1
Ligands: NA
Pockets: 2 · best druggability 0.57

Structure

x-ray diffraction · 2 distinct chains · 33% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hit family hydrolase	protein	143	32% helix, 24% strand	Q5E3V1
B	Hit family hydrolase	protein	139	33% helix, 24% strand	Q5E3V1

Ligands and binding sites

NA · Sodium ion · metal · 19 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	224	0.57	0.79	24	NA
2	182	0.52	0.78	23	empty

Interfaces

1 interface between chains.

A–B · 1422 Å² buried · 30 hydrogen bonds · protein-protein

Compared structures

3I24 · Crystal Structure of a HIT family hydrolase protein from Vibrio fischeri. Northeast… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5E3V1
Elsewhere: RCSB PDB 3I24 · PDBe 3I24 · UniProt Q5E3V1

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