MolNFT v1 · #66811 · protein
Crystal structure of human bfl-1 in complex with bak BH3 peptide
3I1H · Protein bfl-1: “Crystal structure of human bfl-1 in complex with bak BH3 peptide”. X-ray diffraction. MolNFT v1 #66811 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3I1H
- Type
- protein
- Length
- 158 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein bfl-1; Apoptosis regulator bak
- UniProt
- Q16548, Q16611
Structure
x-ray diffraction · 2 distinct chains · 78% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein bfl-1 | protein | 142 | 77% helix, 0% strand | Q16548 |
| B | Apoptosis regulator bak | protein | 16 | 88% helix, 0% strand | Q16611 |
Interfaces
1 interface between chains.
- A–B · 763 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (oxidation).
Compared structures
- 3I1H · Crystal structure of human BFL-1 in complex with BAK BH3 peptide · the same entry in another collection · chain A against A, TM-score 1.00
- Q16548 · AlphaFold monomer V2.0 prediction for BCL-2-related protein A1 (Q16548) · a predicted model of the same protein · chain A against A, TM-score 0.97
- Q16611 · AlphaFold monomer V2.0 prediction for BCL-2 homologous ANTAGONIST/KILLER (Q16611) · a predicted model of the same protein · chain B against A, TM-score 0.74
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q16548
- Every structure of UniProt Q16611
- Elsewhere: RCSB PDB 3I1H · PDBe 3I1H · UniProt Q16548 · UniProt Q16611
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