MolNFT v1 · #66618 · protein

Crystal structure of cytotoxin protein suilysin from streptococcus suis

3HVN · Hemolysin: “Crystal structure of cytotoxin protein suilysin from streptococcus suis”. X-ray diffraction, 2 ligands (CFH, HTO), 5 pockets (best druggability 0.62). MolNFT v1 #66618 on GenesisL1: 3D structure, binding sites and…

PDB: 3HVN
Type: protein
Length: 466 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hemolysin
UniProt: Q55996
Ligands: CFH, HTO
Pockets: 5 · best druggability 0.62

Structure

x-ray diffraction · 1 distinct chain · 18% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hemolysin	protein	466	18% helix, 43% strand	Q55996

Ligands and binding sites

CFH · 1,1,1,3,3,3-hexafluoropropan-2-ol · ligand · chains A
HTO · Heptane-1,2,3-triol · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	177	0.62	0.84	32	empty
2	231	0.59	0.80	30	empty
3	50	0.45	0.85	20	empty
4	102	0.41	0.77	17	empty
5	50	0.29	0.75	14	CFH

Compared structures

3HVN · Crystal structure of cytotoxin protein suilysin from Streptococcus suis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q55996
Elsewhere: RCSB PDB 3HVN · PDBe 3HVN · UniProt Q55996

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