MolNFT v1 · #66604 · protein

Crystal structure of fimx eal domain from pseudomonas aeruginosa bound to C-di-gmp

3HV8 · Protein fimx: “Crystal structure of fimx eal domain from pseudomonas aeruginosa bound to C-di-gmp”. X-ray diffraction, 1 ligand (C2E), 1 pocket (best druggability 0.60). MolNFT v1 #66604 on GenesisL1: 3D structure, binding sites and…

PDB: 3HV8
Type: protein
Length: 242 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein fimx
EC: 3.1.4.52
UniProt: Q9HUK6
Ligands: C2E
Pockets: 1 · best druggability 0.60

Structure

x-ray diffraction · 1 distinct chain · 44% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein fimx (EC 3.1.4.52)	protein	242	44% helix, 21% strand	Q9HUK6

Ligands and binding sites

C2E · 9,9'-[(2r,3r,3as,5s,7ar,9r,10r,10as,12s,14ar)-3,5,10, 12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3, 2-D:3',2'-J][1,3,7,9,2, 8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one) · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	314	0.60	0.78	38	C2E

Compared structures

3HV8 · Crystal structure of FimX EAL domain from Pseudomonas aeruginosa bound to c-di-GMP · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9HUK6
Elsewhere: RCSB PDB 3HV8 · PDBe 3HV8 · UniProt Q9HUK6

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