MolNFT v1 · #66598 · protein

Crystal structure of signal receiver domain of hd domain-containing protein from pseudomonas fluorescens pf-5

3HV2 · Response REGULATOR/HD domain protein: “Crystal structure of signal receiver domain of hd domain-containing protein from pseudomonas fluorescens pf-5”. X-ray diffraction, 1 ligand (SO4), 3 pockets (best druggability 0.64). MolNFT v1…

PDB: 3HV2
Type: protein
Length: 261 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Response REGULATOR/HD domain protein
UniProt: Q4K707
Ligands: SO4
Pockets: 3 · best druggability 0.64

Structure

x-ray diffraction · 2 distinct chains · 44% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Response REGULATOR/HD domain protein	protein	136	44% helix, 17% strand	Q4K707
B	Response REGULATOR/HD domain protein	protein	125	45% helix, 19% strand	Q4K707

Ligands and binding sites

SO4 · Sulfate ion · ion · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	309	0.64	0.81	31	empty
2	89	0.34	0.74	18	empty
3	54	0.30	0.75	15	empty

Interfaces

1 interface between chains.

A–B · 637 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

3HV2 · Crystal structure of signal receiver domain OF HD domain-containing protein FROM… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4K707
Elsewhere: RCSB PDB 3HV2 · PDBe 3HV2 · UniProt Q4K707

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