MolNFT v1 · #66481 · protein

Crystal structure of staphylococcus aureus protein sarz in sulfenic acid form

3HRM · Hth-type transcriptional regulator sarz: “Crystal structure of staphylococcus aureus protein sarz in sulfenic acid form”. X-ray diffraction, 3 pockets (best druggability 0.52). MolNFT v1 #66481 on GenesisL1: 3D structure, binding…

PDB: 3HRM
Type: protein
Length: 265 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hth-type transcriptional regulator sarz
UniProt: A6QJM6
Pockets: 3 · best druggability 0.52

Structure

x-ray diffraction · 2 distinct chains · 71% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hth-type transcriptional regulator sarz	protein	131	72% helix, 5% strand	A6QJM6
B	Hth-type transcriptional regulator sarz	protein	134	69% helix, 7% strand	A6QJM6

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	138	0.52	0.80	18	empty
2	132	0.51	0.79	16	empty
3	153	0.45	0.75	18	empty

Interfaces

1 interface between chains.

A–B · 2599 Å² buried · 12 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 modified (engineered, oxidation).

Compared structures

3HRM · Crystal structure of Staphylococcus aureus protein SarZ in sulfenic acid form · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A6QJM6
Elsewhere: RCSB PDB 3HRM · PDBe 3HRM · UniProt A6QJM6

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