MolNFT v1 · #6643 · protein
Three dimensional structure of beta-acrosin from boar spermatozoa
1FIZ · Beta-acrosin heavy chain: “Three dimensional structure of beta-acrosin from boar spermatozoa”. X-ray diffraction, 6 ligands (PBZ, NAG, NDG), 1 pocket (best druggability 0.60). MolNFT v1 #6643 on GenesisL1: 3D structure, binding…
- PDB
- 1FIZ
- Type
- protein
- Length
- 276 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta-acrosin heavy chain; Beta-acrosin light chain
- UniProt
- P08001
- Ligands
- PBZ, NAG, NDG, BMA, FUL, SO4
- Pockets
- 1 · best druggability 0.60
Structure
x-ray diffraction · 2 distinct chains · 9% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Beta-acrosin heavy chain | protein | 263 | 9% helix, 37% strand | P08001 |
| L | Beta-acrosin light chain | protein | 13 | 0% helix, 0% strand | P08001 |
Ligands and binding sites
- PBZ · P-amino benzamidine · ligand · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
- NDG · 2-acetamido-2-deoxy-alpha-D-glucopyranose · sugar
- BMA · beta-D-mannopyranose · sugar
- FUL · beta-L-fucopyranose · sugar · chains A
- SO4 · Sulfate ion · ion · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 271 | 0.60 | 0.79 | 27 | empty |
Interfaces
1 interface between chains.
- A–L · 727 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide, 1 glycan (disulfide, N-glycosylation).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08001
- Elsewhere: RCSB PDB 1FIZ · PDBe 1FIZ · UniProt P08001
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.