MolNFT v1 · #66406 · protein

Structure of hydroxyethylthiazole kinase protein from pyrococcus horikoshii OT3

3HPD: “Structure of hydroxyethylthiazole kinase protein from pyrococcus horikoshii OT3”. X-ray diffraction, 1 ligand (PO4), 1 pocket (best druggability 0.49). MolNFT v1 #66406 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3HPD
Type: protein
Length: 254 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hydroxyethylthiazole kinase
EC: 2.7.1.50
UniProt: O58877
Ligands: PO4
Pockets: 1 · best druggability 0.49

Structure

x-ray diffraction · 1 distinct chain · 58% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hydroxyethylthiazole kinase (EC 2.7.1.50)	protein	254	58% helix, 17% strand	O58877

Ligands and binding sites

PO4 · Phosphate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	158	0.49	0.78	25	PO4

Compared structures

3HPD · Structure of hydroxyethylthiazole kinase protein from pyrococcus horikoshii OT3 · the same entry in another collection · chain A against A, TM-score 1.00
O58877 · AlphaFold monomer V2.0 prediction for hydroxyethylthiazole kinase (O58877) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O58877
Elsewhere: RCSB PDB 3HPD · PDBe 3HPD · UniProt O58877

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