MolNFT v1 · #66378 · protein
Crystal structure of a novel engineered retroaldolase: ra-22
3HOJ · Retroaldolase-22: “Crystal structure of a novel engineered retroaldolase: ra-22”. X-ray diffraction, 2 pockets (best druggability 0.76). MolNFT v1 #66378 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3HOJ
- Type
- protein
- Length
- 247 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Retroaldolase-22
- EC
- 4.1.1.48
- Pockets
- 2 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Retroaldolase-22 (EC 4.1.1.48) | protein | 247 | 38% helix, 17% strand | — |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 270 | 0.76 | 0.89 | 39 | empty |
| 2 | 52 | 0.23 | 0.72 | 13 | empty |
Compared structures
- 3HOJ · Crystal Structure of a Novel Engineered Retroaldolase: RA-22 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 3HOJ · PDBe 3HOJ
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