MolNFT v1 · #66203 · protein
A rigid N-terminal clamp restrains the motor domains of the bacterial transcription-repair coupling factor
3HJH · Transcription-repair-coupling factor: “A rigid N-terminal clamp restrains the motor domains of the bacterial transcription-repair coupling factor”. X-ray diffraction, 1 ligand (CO), 4 pockets (best druggability 0.54). MolNFT v1…
- PDB
- 3HJH
- Type
- protein
- Length
- 446 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcription-repair-coupling factor
- EC
- 3.6.1.-
- UniProt
- P30958
- Ligands
- CO
- Pockets
- 4 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcription-repair-coupling factor (EC 3.6.1.-) | protein | 446 | 33% helix, 21% strand | P30958 |
Ligands and binding sites
- CO · Cobalt (II) ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 135 | 0.54 | 0.81 | 16 | empty |
| 2 | 119 | 0.43 | 0.77 | 24 | empty |
| 3 | 107 | 0.41 | 0.76 | 22 | empty |
| 4 | 68 | 0.36 | 0.77 | 11 | empty |
Compared structures
- 3HJH · A rigid N-terminal clamp restrains the motor domains of the bacterial… · the same entry in another collection · chain A against A, TM-score 1.00
- P30958 · AlphaFold monomer V2.0 prediction for transcription-repair-coupling factor (P30958) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P30958
- Elsewhere: RCSB PDB 3HJH · PDBe 3HJH · UniProt P30958
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.