MolNFT v1 · #65756 · protein
Structure of the calx-beta domain of integrin BETA4 crystallized in the presence of calcium
3H6A · Integrin beta-4: “Structure of the calx-beta domain of integrin BETA4 crystallized in the presence of calcium”. X-ray diffraction, 1 pocket (best druggability 0.48). MolNFT v1 #65756 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3H6A
- Type
- protein
- Length
- 224 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Integrin beta-4
- UniProt
- P16144
- Pockets
- 1 · best druggability 0.48
Structure
x-ray diffraction · 2 distinct chains · 1% helix, 57% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Integrin beta-4 | protein | 109 | 3% helix, 59% strand | P16144 |
| B | Integrin beta-4 | protein | 115 | 0% helix, 55% strand | P16144 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 121 | 0.48 | 0.79 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 535 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 3H6A · Structure of the Calx-beta domain of integrin beta4 crystallized in the presence of… · the same entry in another collection · chain A against A, TM-score 1.00
- P16144 · AlphaFold monomer V2.0 prediction for integrin beta-4 (P16144) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16144
- Elsewhere: RCSB PDB 3H6A · PDBe 3H6A · UniProt P16144
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.