MolNFT v1 · #65509 · protein
Crystal structure of ipgc in complex with an ipab peptide
3GZ2 · Chaperone protein ipgc: “Crystal structure of ipgc in complex with an ipab peptide”. X-ray diffraction, 3 pockets (best druggability 0.56). MolNFT v1 #65509 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3GZ2
- Type
- protein
- Length
- 294 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chaperone protein ipgc; Invasin ipab
- UniProt
- P0A2U4, P18011
- Pockets
- 3 · best druggability 0.56
Structure
x-ray diffraction · 3 distinct chains · 75% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chaperone protein ipgc | protein | 144 | 78% helix, 0% strand | P0A2U4 |
| B | Chaperone protein ipgc | protein | 143 | 76% helix, 0% strand | P0A2U4 |
| P | Invasin ipab | protein | 7 | 0% helix, 0% strand | P18011 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 249 | 0.56 | 0.78 | 30 | GOL |
| 2 | 89 | 0.51 | 0.83 | 14 | empty |
| 3 | 93 | 0.45 | 0.80 | 23 | empty |
Interfaces
2 interfaces between chains.
- A–B · 1483 Ų buried · 10 hydrogen bonds · protein-protein
- B–P · 471 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 3GZ2 · Crystal structure of IpgC in complex with an IpaB peptide · the same entry in another collection · chain A against A, TM-score 1.00
- P0A2U4 · AlphaFold monomer V2.0 prediction for chaperone protein ipgc (P0A2U4) · a predicted model of the same protein · chain B against A, TM-score 0.90
- P18011 · AlphaFold monomer V2.0 prediction for invasin ipab (P18011) · a predicted model of the same protein · chain P against A, TM-score 0.32
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A2U4
- Every structure of UniProt P18011
- Elsewhere: RCSB PDB 3GZ2 · PDBe 3GZ2 · UniProt P0A2U4 · UniProt P18011
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.