MolNFT v1 · #65135 · protein

Crystal structure of a DUF574 family protein (SAV_2177) from streptomyces avermitilis ma-4680 at 1.80 a resolution

3GO4 · Protein of unknown function DUF574: “Crystal structure of a DUF574 family protein (SAV_2177) from streptomyces avermitilis ma-4680 at 1.80 a…”. X-ray diffraction, 2 ligands (SAH, SO4), 1 pocket (best druggability 0.76). MolNFT v1…

PDB: 3GO4
Type: protein
Length: 262 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein of unknown function DUF574
UniProt: Q82L35
Ligands: SAH, SO4
Pockets: 1 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein of unknown function DUF574	protein	262	42% helix, 15% strand	Q82L35

Ligands and binding sites

SAH · S-adenosyl-L-homocysteine · ligand · chains A
SO4 · Sulfate ion · ion · chains A
EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	384	0.76	0.86	55	SAH

Modifications

Observed in the structure: 8 modified (engineered).

Compared structures

3GO4 · Crystal structure of a duf574 family protein (sav_2177) from streptomyces avermitilis… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q82L35
Elsewhere: RCSB PDB 3GO4 · PDBe 3GO4 · UniProt Q82L35

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.