MolNFT v1 · #64856 · protein
Structure of the C-terminal domain of the dead-box protein DBP5
3GFP · Dead box protein 5: “Structure of the C-terminal domain of the dead-box protein DBP5”. X-ray diffraction, 1 pocket (best druggability 0.36). MolNFT v1 #64856 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3GFP
- Type
- protein
- Length
- 180 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dead box protein 5
- EC
- 3.6.1.-
- UniProt
- P20449
- Pockets
- 1 · best druggability 0.36
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dead box protein 5 (EC 3.6.1.-) | protein | 180 | 38% helix, 20% strand | P20449 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 63 | 0.36 | 0.78 | 14 | empty |
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 3GFP · Structure of the C-terminal domain of the DEAD-box protein Dbp5 · the same entry in another collection · chain A against A, TM-score 1.00
- P20449 · AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase DBP5 (P20449) · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P20449
- Elsewhere: RCSB PDB 3GFP · PDBe 3GFP · UniProt P20449
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