MolNFT v1 · #64615 · protein
Crystal structure of murine natural killer cell receptor, LY49L4
3G8L · Lectin-related nk cell receptor LY49L1: “Crystal structure of murine natural killer cell receptor, LY49L4”. X-ray diffraction, 7 pockets (best druggability 0.44). MolNFT v1 #64615 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3G8L
- Type
- protein
- Length
- 624 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lectin-related nk cell receptor LY49L1
- UniProt
- Q9JIP9
- Pockets
- 7 · best druggability 0.44
Structure
x-ray diffraction · 4 distinct chains · 26% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lectin-related nk cell receptor LY49L1 | protein | 157 | 28% helix, 35% strand | Q9JIP9 |
| B | Lectin-related nk cell receptor LY49L1 | protein | 161 | 27% helix, 33% strand | Q9JIP9 |
| C | Lectin-related nk cell receptor LY49L1 | protein | 154 | 25% helix, 25% strand | Q9JIP9 |
| D | Lectin-related nk cell receptor LY49L1 | protein | 152 | 24% helix, 31% strand | Q9JIP9 |
Pockets
7 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 87 | 0.44 | 0.80 | 22 | empty |
| 2 | 82 | 0.44 | 0.80 | 20 | empty |
| 3 | 53 | 0.39 | 0.81 | 14 | empty |
| 4 | 52 | 0.36 | 0.80 | 15 | empty |
| 5 | 53 | 0.36 | 0.79 | 22 | empty |
Interfaces
3 interfaces between chains.
- B–D · 1846 Ų buried · 10 hydrogen bonds · protein-protein
- A–C · 1670 Ų buried · 11 hydrogen bonds · protein-protein
- A–B · 14 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 17 disulfide (disulfide).
Compared structures
- 3G8L · Crystal structure of murine natural killer cell receptor, Ly49L4 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9JIP9
- Elsewhere: RCSB PDB 3G8L · PDBe 3G8L · UniProt Q9JIP9
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