MolNFT v1 · #64514 · protein
Crystal structure of putative S-adenosylmethionine dependent methyltransferase from listeria monocytogenes
3G5L: “Crystal structure of putative S-adenosylmethionine dependent methyltransferase from listeria monocytogenes”. X-ray diffraction, 1 ligand (CL), 3 pockets (best druggability 0.55). MolNFT v1 #64514 on GenesisL1: 3D structure, binding…
- PDB
- 3G5L
- Type
- protein
- Length
- 435 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative S-adenosylmethionine dependent methyltransferase
- UniProt
- Q720B4
- Ligands
- CL
- Pockets
- 3 · best druggability 0.55
Structure
x-ray diffraction · 2 distinct chains · 29% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative S-adenosylmethionine dependent methyltransferase | protein | 222 | 32% helix, 32% strand | Q720B4 |
| B | Putative S-adenosylmethionine dependent methyltransferase | protein | 213 | 27% helix, 33% strand | Q720B4 |
Ligands and binding sites
- CL · Chloride ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 372 | 0.55 | 0.74 | 47 | empty |
| 2 | 92 | 0.48 | 0.81 | 19 | empty |
| 3 | 169 | 0.43 | 0.74 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 1387 Ų buried · 38 hydrogen bonds · protein-protein
Compared structures
- 3G5L · Crystal structure of putative S-adenosylmethionine dependent methyltransferase from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q720B4
- Elsewhere: RCSB PDB 3G5L · PDBe 3G5L · UniProt Q720B4
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