MolNFT v1 · #64500 · protein
Structure of the macrolide biosensor protein, MPHR(A)
3G56 · Regulator of macrolide 2'-phosphotransferase I: “Structure of the macrolide biosensor protein, MPHR(A)”. X-ray diffraction, 1 pocket (best druggability 0.85). MolNFT v1 #64500 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 3G56
- Type
- protein
- Length
- 359 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Regulator of macrolide 2'-phosphotransferase I
- UniProt
- Q9EVJ6
- Pockets
- 1 · best druggability 0.85
Structure
x-ray diffraction · 2 distinct chains · 73% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulator of macrolide 2'-phosphotransferase I | protein | 180 | 74% helix, 0% strand | Q9EVJ6 |
| B | Regulator of macrolide 2'-phosphotransferase I | protein | 179 | 73% helix, 0% strand | Q9EVJ6 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1025 | 0.85 | 0.85 | 86 | EDO |
Interfaces
1 interface between chains.
- A–B · 1487 Ų buried · 25 hydrogen bonds · protein-protein
Compared structures
- 3G56 · Structure of the macrolide biosensor protein, MphR(A) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9EVJ6
- Elsewhere: RCSB PDB 3G56 · PDBe 3G56 · UniProt Q9EVJ6
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