MolNFT v1 · #64415 · protein
Crystal structure of the glycopeptide N-methyltransferase mtfa
3G2M · PCZA361.24: “Crystal structure of the glycopeptide N-methyltransferase mtfa”. X-ray diffraction, 6 pockets (best druggability 0.68). MolNFT v1 #64415 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3G2M
- Type
- protein
- Length
- 446 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- PCZA361.24
- UniProt
- O52805
- Pockets
- 6 · best druggability 0.68
Structure
x-ray diffraction · 2 distinct chains · 32% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | PCZA361.24 | protein | 232 | 31% helix, 33% strand | O52805 |
| B | PCZA361.24 | protein | 214 | 32% helix, 36% strand | O52805 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 677 | 0.68 | 0.76 | 73 | empty |
| 2 | 182 | 0.53 | 0.79 | 31 | empty |
| 3 | 96 | 0.37 | 0.75 | 22 | empty |
| 4 | 84 | 0.35 | 0.75 | 20 | empty |
| 5 | 88 | 0.31 | 0.73 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 1557 Ų buried · 32 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 modified (engineered).
Compared structures
- 3G2M · Crystal Structure of the Glycopeptide N-methyltransferase MtfA · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O52805
- Elsewhere: RCSB PDB 3G2M · PDBe 3G2M · UniProt O52805
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.