MolNFT v1 · #64365 · protein
Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum
3G18 · Orotidine 5'-phosphate decarboxylase: “Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum”. X-ray diffraction, 2 pockets (best druggability 0.66). MolNFT v1 #64365 on GenesisL1…
- PDB
- 3G18
- Type
- protein
- Length
- 422 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Orotidine 5'-phosphate decarboxylase
- EC
- 4.1.1.23
- UniProt
- O26232
- Pockets
- 2 · best druggability 0.66
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) | protein | 211 | 50% helix, 18% strand | O26232 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 249 | 0.66 | 0.83 | 30 | empty |
| 2 | 236 | 0.63 | 0.82 | 31 | empty |
Interfaces
1 interface between chains.
- A–B · 1615 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 3G18 · Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O26232
- Elsewhere: RCSB PDB 3G18 · PDBe 3G18 · UniProt O26232
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