MolNFT v1 · #64359 · protein

Crystal structure of a putative lactoylglutathione lyase from bdellovibrio bacteriovorus

3G12: “Crystal structure of a putative lactoylglutathione lyase from bdellovibrio bacteriovorus”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.62). MolNFT v1 #64359 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 3G12
Type: protein
Length: 223 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative lactoylglutathione lyase
UniProt: Q6MK89
Ligands: SO4
Pockets: 2 · best druggability 0.62

Structure

x-ray diffraction · 2 distinct chains · 17% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative lactoylglutathione lyase	protein	110	17% helix, 46% strand	Q6MK89
B	Putative lactoylglutathione lyase	protein	113	17% helix, 46% strand	Q6MK89

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	235	0.62	0.81	33	SO4
2	60	0.30	0.75	23	empty

Interfaces

1 interface between chains.

A–B · 1466 Å² buried · 30 hydrogen bonds · protein-protein

Compared structures

3G12 · Crystal structure of a putative lactoylglutathione lyase from Bdellovibrio bacteriovorus · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6MK89
Elsewhere: RCSB PDB 3G12 · PDBe 3G12 · UniProt Q6MK89

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