MolNFT v1 · #64224 · protein
Structure of a putative camp-binding regulatory protein from silicibacter pomeroyi dss-3
3FX3 · Cyclic nucleotide-binding protein: “Structure of a putative camp-binding regulatory protein from silicibacter pomeroyi dss-3”. X-ray diffraction, 1 ligand (PO4), 2 pockets (best druggability 0.71). MolNFT v1 #64224 on GenesisL1: 3D…
- PDB
- 3FX3
- Type
- protein
- Length
- 449 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cyclic nucleotide-binding protein
- UniProt
- Q5LKQ8
- Ligands
- PO4
- Pockets
- 2 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 44% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cyclic nucleotide-binding protein | protein | 218 | 45% helix, 24% strand | Q5LKQ8 |
| B | Cyclic nucleotide-binding protein | protein | 231 | 42% helix, 24% strand | Q5LKQ8 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 659 | 0.71 | 0.78 | 68 | empty |
| 2 | 678 | 0.69 | 0.77 | 66 | PO4 |
Interfaces
1 interface between chains.
- A–B · 2089 Ų buried · 25 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 modified, 2 disulfide (engineered, disulfide).
Compared structures
- 3FX3 · Structure of a putative cAMP-binding regulatory protein from Silicibacter pomeroyi DSS-3 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5LKQ8
- Elsewhere: RCSB PDB 3FX3 · PDBe 3FX3 · UniProt Q5LKQ8
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