MolNFT v1 · #63948 · protein
Crystal structure of TOM71 complexed with SSA1 C-terminal fragment
3FP4 · Tpr repeat-containing protein YHR117W: “Crystal structure of TOM71 complexed with SSA1 C-terminal fragment”. X-ray diffraction, 3 ligands (NA, CL, SO4), 4 pockets (best druggability 0.62). MolNFT v1 #63948 on GenesisL1: 3D…
- PDB
- 3FP4
- Type
- protein
- Length
- 490 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tpr repeat-containing protein YHR117W; SSA1
- UniProt
- P38825
- Ligands
- NA, CL, SO4
- Pockets
- 4 · best druggability 0.62
Structure
x-ray diffraction · 2 distinct chains · 76% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tpr repeat-containing protein YHR117W | protein | 483 | 77% helix, 0% strand | P38825 |
| Q | SSA1 | protein | 7 | 0% helix, 0% strand | — |
Ligands and binding sites
- NA · Sodium ion · metal · 3 copies · chains A
- CL · Chloride ion · ion · 11 copies · chains A
- SO4 · Sulfate ion · ion · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 478 | 0.62 | 0.76 | 58 | NA |
| 2 | 104 | 0.46 | 0.79 | 16 | empty |
| 3 | 109 | 0.44 | 0.78 | 23 | SO4 |
| 4 | 103 | 0.40 | 0.76 | 19 | NA |
Interfaces
1 interface between chains.
- A–Q · 360 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P38825
- Elsewhere: RCSB PDB 3FP4 · PDBe 3FP4 · UniProt P38825
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