MolNFT v1 · #63947 · protein

Crystal structure of TOM71

3FP3 · Tpr repeat-containing protein YHR117W: “Crystal structure of TOM71”. X-ray diffraction, 2 ligands (CL, SO4), 8 pockets (best druggability 0.66). MolNFT v1 #63947 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3FP3
Type: protein
Length: 498 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tpr repeat-containing protein YHR117W
UniProt: P38825
Ligands: CL, SO4
Pockets: 8 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 77% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tpr repeat-containing protein YHR117W	protein	498	77% helix, 0% strand	P38825

Ligands and binding sites

CL · Chloride ion · ion · 4 copies · chains A
SO4 · Sulfate ion · ion · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	640	0.66	0.75	62	empty
2	125	0.51	0.81	23	empty
3	119	0.46	0.78	19	SO4, CL
4	113	0.45	0.78	17	empty
5	76	0.33	0.74	15	SO4

Compared structures

3FP3 · Crystal structure of Tom71 · the same entry in another collection · chain A against A, TM-score 1.00
P38825 · AlphaFold monomer V2.0 prediction for protein TOM71 (P38825) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P38825
Elsewhere: RCSB PDB 3FP3 · PDBe 3FP3 · UniProt P38825

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