MolNFT v1 · #63886 · protein
Apo-form of NAD-dependent formate dehydrogenase from bacterium moraxella SP.C-1 in closed conformation
3FN4: “Apo-form of NAD-dependent formate dehydrogenase from bacterium moraxella SP.C-1 in closed conformation”. X-ray diffraction, 1 ligand (SO4), 4 pockets (best druggability 0.72). MolNFT v1 #63886 on GenesisL1: 3D structure, binding…
- PDB
- 3FN4
- Type
- protein
- Length
- 399 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- NAD-dependent formate dehydrogenase
- EC
- 1.2.1.2
- UniProt
- O08375
- Ligands
- SO4
- Pockets
- 4 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NAD-dependent formate dehydrogenase (EC 1.2.1.2) | protein | 399 | 35% helix, 17% strand | O08375 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 365 | 0.72 | 0.84 | 47 | GOL, SO4 |
| 2 | 214 | 0.54 | 0.77 | 22 | empty |
| 3 | 94 | 0.43 | 0.78 | 20 | empty |
| 4 | 79 | 0.34 | 0.74 | 13 | empty |
Compared structures
- 3FN4 · Apo-form of NAD-dependent formate dehydrogenase from bacterium Moraxella sp.C-1 in closed… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O08375
- Elsewhere: RCSB PDB 3FN4 · PDBe 3FN4 · UniProt O08375
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