MolNFT v1 · #63716 · protein

Nhaa dimer model

3FI1 · NA(+)/H(+) antiporter nhaa: “Nhaa dimer model”. Electron crystallography, 7 pockets (best druggability 0.67). MolNFT v1 #63716 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3FI1
Type: protein
Length: 376 residues
Chains: 1
Method: electron crystallography
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: NA(+)/H(+) antiporter nhaa
UniProt: P13738
Pockets: 7 · best druggability 0.67

Structure

electron crystallography · 1 distinct chain · 61% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	NA(+)/H(+) antiporter nhaa	protein	376	61% helix, 2% strand	P13738

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	294	0.67	0.82	29	empty
2	410	0.66	0.79	44	empty
3	141	0.47	0.77	26	empty
4	134	0.45	0.76	20	empty
5	59	0.37	0.79	13	empty

Compared structures

3FI1 · NhaA dimer model · the same entry in another collection · chain A against A, TM-score 1.00
P13738 · AlphaFold monomer V2.0 prediction for NA(+)/H(+) antiporter nhaa (P13738) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P13738
Elsewhere: RCSB PDB 3FI1 · PDBe 3FI1 · UniProt P13738

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