MolNFT v1 · #63616 · protein
Crystal structure of a phenazine biosynthesis-related protein (PHZB2) from pseudomonas aeruginosa at 1.90 a resolution
3FF0 · Phenazine biosynthesis protein phzb 2: “Crystal structure of a phenazine biosynthesis-related protein (PHZB2) from pseudomonas aeruginosa at 1.90 a…”. X-ray diffraction, 1 ligand (UNL), 3 pockets (best druggability 0.83). MolNFT v1…
- PDB
- 3FF0
- Type
- protein
- Length
- 316 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phenazine biosynthesis protein phzb 2
- UniProt
- Q9S508
- Ligands
- UNL
- Pockets
- 3 · best druggability 0.83
Structure
x-ray diffraction · 2 distinct chains · 32% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phenazine biosynthesis protein phzb 2 | protein | 162 | 30% helix, 36% strand | Q9S508 |
| B | Phenazine biosynthesis protein phzb 2 | protein | 154 | 33% helix, 38% strand | Q9S508 |
Ligands and binding sites
- UNL · Unknown ligand · ligand · 2 copies · chains A, B
- GOL · Glycerol · additive · 7 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 187 | 0.83 | 0.97 | 29 | UNL, GOL |
| 2 | 194 | 0.82 | 0.96 | 32 | UNL, GOL |
| 3 | 65 | 0.41 | 0.80 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 2578 Ų buried · 29 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 3FF0 · Crystal structure of a phenazine biosynthesis-related protein (phzb2) from pseudomonas… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9S508 · AlphaFold monomer V2.0 prediction for phenazine biosynthesis protein PHZB2 (Q9S508) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9S508
- Elsewhere: RCSB PDB 3FF0 · PDBe 3FF0 · UniProt Q9S508
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