MolNFT v1 · #63586 · protein
Crystal structure of 3-hydroxyanthranilate 3,4-dioxygenase from bovine kidney
3FE5: “Crystal structure of 3-hydroxyanthranilate 3,4-dioxygenase from bovine kidney”. X-ray diffraction, 1 ligand (FE), 3 pockets (best druggability 0.75). MolNFT v1 #63586 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3FE5
- Type
- protein
- Length
- 283 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3-hydroxyanthranilate 3,4-dioxygenase
- EC
- 1.13.11.6
- UniProt
- Q0VCA8
- Ligands
- FE
- Pockets
- 3 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 15% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) | protein | 283 | 15% helix, 43% strand | Q0VCA8 |
Ligands and binding sites
- FE · Fe (III) ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 77 | 0.75 | 0.98 | 19 | empty |
| 2 | 72 | 0.41 | 0.79 | 18 | empty |
| 3 | 89 | 0.35 | 0.75 | 18 | empty |
Modifications
Observed in the structure: 3 modified (oxidation).
Compared structures
- 3FE5 · Crystal structure of 3-hydroxyanthranilate 3,4-dioxygenase from bovine kidney · the same entry in another collection · chain A against A, TM-score 1.00
- Q0VCA8 · AlphaFold monomer V2.0 prediction for 3-hydroxyanthranilate 3,4-dioxygenase (Q0VCA8) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q0VCA8
- Elsewhere: RCSB PDB 3FE5 · PDBe 3FE5 · UniProt Q0VCA8
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