MolNFT v1 · #63555 · protein
Crystal structure of onconase C87A/C104A-onc
3FD7 · Protein P-30: “Crystal structure of onconase C87A/C104A-onc”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.67). MolNFT v1 #63555 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3FD7
- Type
- protein
- Length
- 206 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein P-30
- EC
- 3.1.27.-
- UniProt
- P22069
- Ligands
- SO4
- Pockets
- 1 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 19% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Protein P-30 (EC 3.1.27.-) | protein | 103 | 19% helix, 41% strand | P22069 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 7 copies · chains A, B
- GOL · Glycerol · additive · 3 copies · chains A, B
- EDO · 1,2-ethanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 725 | 0.67 | 0.75 | 64 | SO4, GOL |
Interfaces
1 interface between chains.
- A–B · 455 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide, 2 modified (disulfide, cyclization).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22069
- Elsewhere: RCSB PDB 3FD7 · PDBe 3FD7 · UniProt P22069
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.