MolNFT v1 · #63526 · protein
Crystal structure of a putative glyoxalase from an environmental bacteria
3FCD · Lyase: “Crystal structure of a putative glyoxalase from an environmental bacteria”. X-ray diffraction, 3 pockets (best druggability 0.52). MolNFT v1 #63526 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3FCD
- Type
- protein
- Length
- 236 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lyase
- UniProt
- Q93AH5
- Pockets
- 3 · best druggability 0.52
Structure
x-ray diffraction · 2 distinct chains · 22% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lyase | protein | 117 | 22% helix, 45% strand | Q93AH5 |
| B | Lyase | protein | 119 | 22% helix, 42% strand | Q93AH5 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 222 | 0.52 | 0.76 | 32 | empty |
| 2 | 133 | 0.51 | 0.80 | 21 | empty |
| 3 | 131 | 0.40 | 0.74 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 1352 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 3FCD · Crystal Structure of a putative glyoxalase from an environmental bacteria · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q93AH5
- Elsewhere: RCSB PDB 3FCD · PDBe 3FCD · UniProt Q93AH5
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