MolNFT v1 · #63456 · protein
Crystal structure of the apo R132K:Y134F:R111L:L121E mutant of cellular retinoic acid-binding protein II at 1.78 ångström resolution
3FA8 · Cellular retinoic acid-binding protein 2: “Crystal structure of the apo R132K:Y134F:R111L:L121E mutant of cellular retinoic acid-binding protein II at…”. X-ray diffraction, 3 pockets (best druggability 0.76). MolNFT v1 #63456 on…
- PDB
- 3FA8
- Type
- protein
- Length
- 274 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cellular retinoic acid-binding protein 2
- UniProt
- P29373
- Pockets
- 3 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 13% helix, 55% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Cellular retinoic acid-binding protein 2 | protein | 137 | 13% helix, 55% strand | P29373 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 534 | 0.76 | 0.83 | 45 | empty |
| 2 | 592 | 0.75 | 0.81 | 47 | empty |
| 3 | 131 | 0.43 | 0.76 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 38 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 3FA8 · Crystal structure of the apo R132K:Y134F:R111L:L121E mutant of cellular retinoic… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29373
- Elsewhere: RCSB PDB 3FA8 · PDBe 3FA8 · UniProt P29373
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