MolNFT v1 · #63427 · protein
Crystal structure of the S139A mutant of SARS-coronovirus 3C-like protease
3F9E · 3C-like proteinase: “Crystal structure of the S139A mutant of SARS-coronovirus 3C-like protease”. X-ray diffraction, 3 pockets (best druggability 0.51). MolNFT v1 #63427 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3F9E
- Type
- protein
- Length
- 297 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3C-like proteinase
- EC
- 3.4.22.-
- UniProt
- P0C6U8
- Pockets
- 3 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 26% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3C-like proteinase (EC 3.4.22.-) | protein | 297 | 26% helix, 30% strand | P0C6U8 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 135 | 0.51 | 0.80 | 23 | empty |
| 2 | 85 | 0.36 | 0.76 | 20 | empty |
| 3 | 67 | 0.28 | 0.73 | 18 | empty |
Compared structures
- 3F9E · Crystal Structure of the S139A mutant of SARS-Coronovirus 3C-like Protease · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0C6U8
- Elsewhere: RCSB PDB 3F9E · PDBe 3F9E · UniProt P0C6U8
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