MolNFT v1 · #63332 · protein

Crystal structure of 2-C-methyl-D-erythritol 2,4- cyclodiphosphate synthase ispf from yersinia pestis

3F6M · 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase: “Crystal structure of 2-C-methyl-D-erythritol 2,4- cyclodiphosphate synthase ispf from yersinia pestis”. X-ray diffraction, 1 pocket (best druggability 0.45). MolNFT v1 #63332…

PDB: 3F6M
Type: protein
Length: 161 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
EC: 4.6.1.12
UniProt: Q8ZBP7
Pockets: 1 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12)	protein	161	34% helix, 29% strand	Q8ZBP7

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	92	0.45	0.80	16	empty

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

3F6M · Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from… · the same entry in another collection · chain A against A, TM-score 1.00
Q8ZBP7 · AlphaFold monomer V2.0 prediction for 2-C-methyl-D-erythritol 2,4-cyclodiphosphate… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8ZBP7
Elsewhere: RCSB PDB 3F6M · PDBe 3F6M · UniProt Q8ZBP7

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