MolNFT v1 · #63320 · protein
Crystal structure of a hydrolase, nudix family from clostridium perfringens
3F6A: “Crystal structure of a hydrolase, nudix family from clostridium perfringens”. X-ray diffraction, 3 pockets (best druggability 0.67). MolNFT v1 #63320 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3F6A
- Type
- protein
- Length
- 295 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hydrolase, nudix family
- UniProt
- Q0TS82
- Pockets
- 3 · best druggability 0.67
Structure
x-ray diffraction · 2 distinct chains · 26% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hydrolase, nudix family | protein | 150 | 23% helix, 29% strand | Q0TS82 |
| B | Hydrolase, nudix family | protein | 145 | 28% helix, 29% strand | Q0TS82 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 243 | 0.67 | 0.84 | 46 | empty |
| 2 | 200 | 0.56 | 0.80 | 32 | empty |
| 3 | 181 | 0.49 | 0.76 | 33 | empty |
Interfaces
1 interface between chains.
- A–B · 1808 Ų buried · 28 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 3F6A · Crystal structure of a hydrolase, NUDIX family from Clostridium perfringens · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q0TS82
- Elsewhere: RCSB PDB 3F6A · PDBe 3F6A · UniProt Q0TS82
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