MolNFT v1 · #63284 · protein
The structure of a previously undetected carboxysome shell protein: CSOS1D from prochlorococcus marinus MED4
3F56: “The structure of a previously undetected carboxysome shell protein: CSOS1D from prochlorococcus marinus MED4”. X-ray diffraction, 17 pockets (best druggability 0.67). MolNFT v1 #63284 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3F56
- Type
- protein
- Length
- 1,232 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- CSOS1D
- UniProt
- Q7V2D3
- Pockets
- 17 · best druggability 0.67
Structure
x-ray diffraction · 5 distinct chains · 40% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | CSOS1D | protein | 207 | 41% helix, 29% strand | Q7V2D3 |
| B | CSOS1D | protein | 209 | 41% helix, 28% strand | Q7V2D3 |
| C | CSOS1D | protein | 208 | 42% helix, 28% strand | Q7V2D3 |
| D, F | CSOS1D | protein | 204 | 39% helix, 29% strand | Q7V2D3 |
| E | CSOS1D | protein | 200 | 39% helix, 30% strand | Q7V2D3 |
Pockets
17 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 340 | 0.67 | 0.81 | 48 | empty |
| 2 | 171 | 0.67 | 0.86 | 25 | empty |
| 3 | 150 | 0.65 | 0.86 | 24 | empty |
| 4 | 244 | 0.64 | 0.82 | 29 | empty |
| 5 | 239 | 0.63 | 0.82 | 33 | empty |
Interfaces
15 interfaces between chains.
- A–B · 1198 Ų buried · 23 hydrogen bonds · protein-protein
- B–C · 1134 Ų buried · 18 hydrogen bonds · protein-protein
- A–C · 1134 Ų buried · 22 hydrogen bonds · protein-protein
- B–F · 998 Ų buried · 15 hydrogen bonds · protein-protein
- C–E · 995 Ų buried · 14 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 42 modified (engineered).
Compared structures
- 3F56 · The structure of a previously undetected carboxysome shell protein: CsoS1D from… · the same entry in another collection · chain F against F, TM-score 1.00
- Q7V2D3 · AlphaFold monomer V2.0 prediction for carboxysome shell protein CSOS1D (Q7V2D3) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7V2D3
- Elsewhere: RCSB PDB 3F56 · PDBe 3F56 · UniProt Q7V2D3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.